Clavulanic Acid Decreases Cocaine Cue Reactivity in Addiction-Related Brain Areas, a Randomized fMRI Pilot Study
CONCLUSION: CLAV reduced the response of the brain regions associated with motivation and emotional response during the DOWN condition compared to PBO, suggesting CLAV may strengthen voluntary efforts to avoid cocaine use. This pilot data supports the use of CLAV for CUD. (Trial registered in ClinicalTrials.gov NCT04411914).PMID:38601830 | PMC:PMC11003254
Source: Psychopharmacology Bulletin - Category: Psychiatry & Psychology Authors: Linda S Callans Helene Philogene-Khalid Kanchana Jagannathan Ronan Cunningham Daohai Yu Xiaoning Lu M Ingre Walters Mary F Morrison Source Type: research