Decoding Myofascial Pain: Windup Phenomenon as A Key Diagnostic Measure

Myofascial pain syndrome (MPS) is a common musculoskeletal pain disorder with increased prevalence in individuals with comorbidities including cancer, stroke, osteoarthritis, mental health conditions, and more. Despite its prevalence, there is a lack of clinically feasible, evidence-based outcome measures for MPS diagnosis. The windup phenomenon is a frequency-dependent increase in neuronal excitability to input stimuli, facilitating temporal summation of pain that's commonly associated with central sensitization.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research