Decoding Myofascial Pain: Windup Phenomenon as A Key Diagnostic Measure
Myofascial pain syndrome (MPS) is a common musculoskeletal pain disorder with increased prevalence in individuals with comorbidities including cancer, stroke, osteoarthritis, mental health conditions, and more. Despite its prevalence, there is a lack of clinically feasible, evidence-based outcome measures for MPS diagnosis. The windup phenomenon is a frequency-dependent increase in neuronal excitability to input stimuli, facilitating temporal summation of pain that's commonly associated with central sensitization.
Source: The Journal of Pain - Category: Materials Science Authors: Yonathan Assefa, John Srbely, Lynn Gerber, Secili DeStefano, Jay Shah, Siddartha Siikdar Source Type: research
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