Longitudinal Lower Airway Microbial Signatures of Acute Cellular Rejection in Lung Transplantation

Purpose: Dynamic changes in the lower airway microbiome after lung transplantation (LT) have been shown to influence immunologic tone within the allograft, although its overall impact on risk for acute cellular rejection (ACR) remains poorly understood. Our study aimed to evaluate whether temporal changes in certain microbial signatures were associated with the development of ACR.

Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , K.K. Wong, N.C. Nelson, B.G. Wu, D. Rudym, M.B. Lesko, S. Qayum, T.C. Lewis, S.H. Chang, J.C. Chan, T.C. Geraci, F.A. Tiripicchio, Y. Li, C. Wang, H. Li, J. Schnier, P. Pamar, I.J. Mahoney, T. Malik, F. Darawshy, I. Sulaiman, R. Singh, D.E. Collazo, M. Source Type: research