Cystatin C-Based Estimated Glomerular Filtration Rate is Independently Associated with Long-Term Mortality in HeartMate3 Patients

Purpose: An accurate assessment of kidney function is of paramount importance in the risk stratification of patients undergoing HeartMate 3 (HM3) implant. In this population, the high prevalence of sarcopenia and malnutrition may bias accuracy of serum creatinine (sCr)-based estimated glomerular filtration rate (eGFRsCr). Cystatin C (cysC)-based eGFR (eGFRcysC), an alternative assessment of kidney function, is less influenced by muscle mass and nutritional status. Herein, we investigated the association of pre-implant eGFRsCr and eGFRcysC with long-term mortality in a cohort of patients implanted with HM3.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research