Nirmatrelvir-Ritonavir Drug Interactions Lead to Multi-Organ Dysfunction in a Lung Transplant Recipient

Introduction: Nirmatrelvir-ritonavir (Paxlovid) therapy for treatment of mild to moderate COVID-19 in lung transplant patients can interact with tacrolimus leading to drug toxicity and organ damage. The appropriate use of Paxlovid in this patient population is of paramount importance.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research