Association of Longitudinal Changes in NT-proBNP Following HeartMate 3 Implant with Subsequent Long-Term Clinical Outcomes

Purpose: Monitoring of natriuretic peptides (NT-proBNP) has prognostic implications in patients with congestive heart failure. The role of serial monitoring of NT-proBNP in patients with a durable left ventricular assist device (LVAD) is not well-defined. We sought to: 1) assess serial trends in NT-proBNP within 3 months after implant; and 2) determine the association between short-term NT-proBNP changes and subsequent long-term risk of right heart failure (RHF), as defined by INTERMACS, and all-cause mortality in patients implanted with the contemporary HeartMate 3 ( ΗΜ3, Αbbott, USA) LVAD.

Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J.D. Alexis, A. Godishala, L. Chen, S. Thomas, M. Tallman, S. McNitt, B. Polonsky, S. Sherazi, K. Wood, I. Gosev, I. Goldenberg Source Type: research