Sweet Surprises: An In-depth Systematic Review of Artificial Sweeteners and Their Association with Cerebrovascular Accidents

AbstractPurpose of ReviewArtificial sweeteners have become increasingly popular in today ’s dietary trends as a healthier and sweeter alternative to sugar. As studies emerge regarding artificial sweeteners, concerns are arising about their side effects, particularly linking them to strokes. This systematic review aims to assess the relationship between artificial sweeteners (AS) and c erebrovascular accidents (CVAs). A systematic search of studies indexed in PubMed and Google Scholar was conducted using the keywords “ASB” (artificially sweetened beverage), “Artificial Sweeteners,” “Stroke,” etc. These studies were screened and filtered according to our exclusion crite ria. We reviewed 55 studies published in various journals and further boiled down to finalizing 12 studies for analysis using the PRISMA Statement (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020.Recent FindingsMost studies suggest that there is a positive association between artificial sweetener consumption and CVAs including all types of strokes, particularly ischemic strokes. Poorer outcomes are seen with higher ASB intake. Increased risk is notable among women and black populations. Some studies show no association between ASB consumption and hemorrhagic stroke, however, most suggest a strong link.SummaryThe current literature shows a degree of variation so it is crucial to consider possible confounders and eliminate them in future studies. Further research is necessary...
Source: Current Nutrition Reports - Category: Nutrition Source Type: research