Insulin ‐like growth factor binding protein‐7 concentrations in chronic heart failure: Results from the EMPEROR programme

ConclusionAcross the entire left ventricular EF spectrum in the EMPEROR Programme, concentrations of the senescence-associated biomarker IGFBP7 were associated with higher risk clinical status and predicted adverse cardio-renal outcomes even in models adjusted for conventional biomarkers. Empagliflozin did not significantly affect IGFBP7 levels over time.

Source: European Journal of Heart Failure - April 9, 2024 Category: Cardiology Authors: Jo ão Pedro Ferreira, Milton Packer, Naveed Sattar, Javed Butler, Sandra González Maldonado, Marina Panova‐Noeva, Mikhail Sumin, Serge Masson, Stuart J. Pocock, Stefan D. Anker, Faiez Zannad, James L. Januzzi Tags: Research Article Source Type: research