Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling

ConclusionDEX promotes CRC progression may via activating α2 adrenoceptor-dependent Nrf2/Piwil2/Siah2 pathway and thus EMT process. Our work provides a novel insight into the mechanism underlying tumor-promoting effects of α2-adrenoceptor agonists.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research