Palmatine inhibits expression fat mass and obesity associated protein (FTO) and exhibits a curative effect in dextran sulfate sodium (DSS)-induced experimental colitis

CONCLUSIONS: The findings demonstrated that PAL improved DSS-induced experimental colitis. This effect was associated with inhibiting FTO expression and regulating m6A methylation.PMID:38579565 | DOI:10.1016/j.intimp.2024.111968

Source: International Immunopharmacology - April 5, 2024 Category: Allergy & Immunology Authors: Wanli Ji Yan Huo Yifan Zhang Xiaojing Qian Yi Ren Cheng Hu Jiaqi Zhang Source Type: research