Glycoursodeoxycholic Acid Alleviates Arterial Thrombosis via Suppressing Diacylglycerol Kinases Activity in Platelet

CONCLUSIONS: Our study implicated that GUDCA reduces platelet hyperreactivity and improves thrombotic propensity by inhibiting DGKs activity, which is a potentially effective prophylactic approach and promising therapeutic agent for arterial thrombotic events.PMID:38572646 | DOI:10.1161/ATVBAHA.124.320728

Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 4, 2024 Category: Cardiology Authors: Wenchao Yang Ruijia Feng Guiyan Peng Zhecun Wang Meifeng Cen Yexiang Jing Weiqi Feng Ting Long Yunchong Liu Zilun Li Kan Huang Guangqi Chang Source Type: research