Genes, Vol. 15, Pages 462: Impact of 12-SNP and 6-SNP Polygenic Scores on Predisposition to High LDL-Cholesterol Levels in Patients with Familial Hypercholesterolemia

Conclusions: The 12-SNP and 6-SNP polygenic scores could explain hypercholesterolemia in patients without pathogenic variants as well as the variability of LDL-c levels among patients with FH-causative variants.

Source: Genes - April 6, 2024 Category: Genetics & Stem Cells Authors: Giovanna Cardiero Martina Ferrandino Ilenia Lorenza Calcaterra Gabriella Iannuzzo Matteo Nicola Dario Di Minno Raffaele Buganza Ornella Guardamagna Renata Auricchio Maria Donata Di Taranto Giuliana Fortunato Tags: Article Source Type: research