High Preformed Vitamin A Intake during Pregnancy Prevents Embryonic Accumulation of Intact {beta}-Carotene from the Maternal Circulation in Mice [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Conclusions: In mice, transfer of intact BC to the embryo is attenuated by high tissue vitamin A concentrations. Maternal vitamin A intake and BC availability activate a placental transcriptional response to protect the embryo from retinoid and carotenoid excess.

Source: Journal of Nutrition - July 1, 2015 Category: Nutrition Authors: Wassef, L., Shete, V., Costabile, B., Rodas, R., Quadro, L. Tags: Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions Source Type: research