Polyethylene glycol hypersensitivity, patient outcomes in a seven year retrospective study

CONCLUSION: PEG hypersensitivity is an uncommon cause of drug-induced anaphylaxis. Four index drugs accounted for two-thirds of cases and reactions to these drugs should prompt PEG hypersensitivity investigations. PEG IDT increases diagnostic yield. The role of SPT with higher MW PEGs requires further attention. Further studies are required to understand PEG thresholds and PEG equivalent doses of various administration routes. COVID-19 vaccines were tolerated by all exposed.PMID:38561050 | DOI:10.1016/j.anai.2024.03.022

Source: Annals of Allergy, Asthma and Immunology - April 1, 2024 Category: Allergy & Immunology Authors: Oyindamola Stephanie Kayode Alla Nakonechna Leonard Quok Chean Siew Magdalena Dziadzio Lucinda Kennard Krzysztof Rutkowski Rita Mirakian Annette Wagner Source Type: research