Proportion of Hypogonadism in Transfusion-Dependent Thalassemia Patients and Its Contributing Factors

CONCLUSION: We confirmed the role of pre-transfusion Hb count as a potential predictor for hypogonadism due to the tissue hypoxia mechanism and transfusion-related iron overload in TDT patients. Decreased Hb is linearly correlated with FSH, LH, and testosterone levels. Decreased Hb also downregulates these factors.PMID:38561881

Source: Acta medica Indonesiana - April 2, 2024 Category: Internal Medicine Authors: Dian Anindita Lubis Imam Subekti Em Yunir Cosphiadi Irawan Andon Hestiantoro Silvia Werdhy Lestari Aria Kekalih Merci Monica Br Pasaribu Santi Syafril Source Type: research