Venom diversity in < i > Naja mossambica < /i > : Insights from proteomic and immunochemical analyses reveal intraspecific differences

Conclusions/SignificanceOur findings reveal a substantial presence of neurotoxic proteins inN.mossambica venoms, challenging previous understandings of their composition. Additionally, the detection of numerous peptides aligning to uncharacterized proteins or proteins with unknown functions underscores a critical issue with existing venom protein databases, emphasizing the substantial gaps in our knowledge of snake venom protein components. This underscores the need for enhanced research in this domain. Moreover, ourin vitro immunological assays suggest EchiTAb+ICP ’s potential as an alternative to SAIMR antivenom, requiring confirmation through prospectivein vivo neutralization studies.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research