Wogonin inhibits the migration and invasion of fibroblast-like synoviocytes by targeting PI3K/AKT/NF- κB pathway in rheumatoid arthritis

CONCLUSION: Wogonin effectively inhibits migration, invasion and pro-inflammatory cytokine production of RA fibroblast-like synoviocytes through the PI3K/AKT/NF-κB pathway, and thus wogonin, as a natural flavonoid, has great potential for treating RA.PMID:38552763 | DOI:10.1016/j.abb.2024.109965

Source: Archives of Biochemistry and Biophysics - March 29, 2024 Category: Biochemistry Authors: Haixin Yang Cuizhen Liu Xiujuan Lin Xing Li Shan Zeng Zhaohui Gong Qiang Xu Detang Li Nan Li Source Type: research