Multi-strain probiotics ameliorates Alzheimer's-like cognitive impairment and pathological changes through the AKT/GSK-3 β pathway in senescence-accelerated mouse prone 8 mice

CONCLUSIONS: Multi-strain probiotics treatment can ameliorate cognitive impairment and pathological change in SAMP8 mice, including neural damage, Aβ and Tau pathology, and neuroinflammation. This effect is associated with the regulation of the phosphorylation of the AKT/GSK-3β pathway.PMID:38548184 | DOI:10.1016/j.bbi.2024.03.031
Source: Brain, Behavior, and Immunity - Category: Neurology Authors: Source Type: research