Similar immune responses to alpha1 ‐oleate and Bacillus Calmette–Guérin treatment in patients with bladder cancer

ConclusionsThe cytokine response profile in alpha 1-oleate treated patients was similar to that reported in BCG treated patients, suggesting a significant overlap. A reduction in protein levels at the end of treatment coincided with inhibition of cancer-related gene expression in tissue biopsies, consistent with a positive treatment effect. Thus, in addition to killing tumor cells and inducing cell detachment, alpha 1-oleate is shown to activate a broad immune response with a protective potential.

Source: Cancer Medicine - March 30, 2024 Category: Cancer & Oncology Authors: Shahram Ahmadi, Ines Ambite, Anton ín Brisuda, Jaromír Háček, Farhan Haq, Samudra Sabari, Kamala Vanarsa, Chandra Mohan, Marek Babjuk, Catharina Svanborg Tags: RESEARCH ARTICLE Source Type: research