Effectiveness and Safety of Different Oral Anticoagulants with P-glycoprotein/ CYP3A4 Inhibitors: A Network Meta-analysis

CONCLUSION: When concomitantly used with P-gp/CYP3A4 inhibitors, apixaban and edoxaban were associated with a lower risk of bleeding, though no significant difference in effectiveness was observed among all OACs.PMID:38523519 | DOI:10.2174/0113816128293940240315073345

Source: Current Pharmaceutical Design - March 25, 2024 Category: Drugs & Pharmacology Authors: Siyu Yang Ye Xu Yang Zhang Dandan Li Xingang Li Source Type: research