TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2
CONCLUSION: Our findings revealed a crucial role for CLCA2 in mediating apoptosis in POI pathogenesis, and suggested that CLCA2 is a potential therapeutic target for POI.PMID:38528613 | PMC:PMC10962206 | DOI:10.1186/s13048-024-01396-2
Source: Cell Research - Category: Cytology Authors: Yali Fan Shuya Chen Chunfang Chu Xiaodan Yin Jing Jin Lingyan Zhang Huihui Yan Zheng Cao Ruixia Liu Mingwei Xin Lin Li Chenghong Yin Source Type: research
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