Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response < em > in vitro < /em >

CONCLUSION: This study proves that both matrine and icariin have inhibitory effects on BVDV replication by activating IFN production and the IFN signalling pathway. The finding is promising and should open up the possibility of larger-scale in vitro research followed by in vivo experiments evaluating matrine and icariin as therapeutic agents in BVD cases.PMID:38525227 | PMC:PMC10960331 | DOI:10.2478/jvetres-2024-0013

Source: Cell Research - March 25, 2024 Category: Cytology Authors: Dongjie Cai Zifan Shen Bin Tian Jie Chen Yilin Zhang Liuhong Shen Ya Wang Xiaoping Ma Zhicai Zuo Source Type: research