Clinical features and surgical treatments of scoliosis in neurofibromatosis type 1: a systemic review and meta-analysis

ConclusionScoliosis, especially the subtype characterized by dystrophic bony changes, is a significant orthopedic manifestation of NF1. It has an early onset, a tendency to persistently and rapidly progress, and is challenging to deal with. The current review outlines the available evidence from the perspective of natural history, clinical features, and the treatment efficacy and safety of the mainstay surgical options. Patients with NF1 scoliosis will benefit from a better understanding of the disease and evidence based treatment strategies.
Source: European Spine Journal - Category: Orthopaedics Source Type: research