Association between CYP4A11 and EPHX2 genetic polymorphisms and chronic kidney disease progression in hypertensive patients

CONCLUSIONS: In this study has been found higher odds of impaired renal function progression associated with rs3890011 and rs9332982 (CYP4A11) and rs41507953 and rs1042032 (EPHX2) polymorphisms, which may serve as biomarkers for improve clinical interventions aimed at avoiding or delaying, in chronic kidney disease patients, progress to end-stage kidney disease needing dialysis or kidney transplant.PMID:38448299 | DOI:10.1016/j.nefroe.2024.01.020

Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - March 6, 2024 Category: Urology & Nephrology Authors: Miguel A Su árez-Santisteban Gracia Santos-D íaz Vanesa Garc ía-Bernalt Ana M P érez-Pico Esther Mingorance Raquel Mayordomo Pedro Dorado Source Type: research