Identification of a mechanism promoting mitochondrial sterol accumulation during myocardial ischemia –reperfusion: role of TSPO and STAR

This study reveals a novel mitochondrial interaction between TSPO and STAR to promote cholesterol and deleterious sterol mitochondrial accumulation during myocardial ischemia–reperfusion. This interaction regulates mitochondrial homeostasis and plays a key role during mitochond rial injury.
Source: Basic Research in Cardiology - Category: Cardiology Source Type: research