NEK2 affects the ferroptosis sensitivity of gastric cancer cells by regulating the expression of HMOX1 through Keap1/Nrf2

This study confirmed that NEK2 can regulate HMOX1 expression through Keap1/Nrf2 signal, and then affect the sensitivity of gastric cancer cells to ferroptosis, enriching the role and mechanism of NEK2 in gastric cancer.PMID:38503948 | DOI:10.1007/s11010-024-04960-y

Source: Molecular and Cellular Biochemistry - March 20, 2024 Category: Biochemistry Authors: Jianyong Wu Desheng Luo Laizhen Tou Hongtao Xu Chuan Jiang Dan Wu Haifeng Que Jingjing Zheng Source Type: research