The role of genetics in the treatment of dystonia with deep brain stimulation: Systematic review and Meta-analysis

Dystonia is a movement disorder characterized by sustained or intermittent muscle contractions that lead to involuntary postures or repetitive movements. Genetic mutations are being increasingly recognized as a cause of dystonia. Deep brain stimulation (DBS) is one of the limited treatment options available. However, there are varying reports on its efficacy in genetic dystonias. This systematic review of the characteristics of genetic dystonias treated with DBS and their outcomes aims to aid in the evaluation of eligibility for such treatment.

Source: Journal of the Neurological Sciences - March 20, 2024 Category: Neurology Authors: Harini Sarva, Federico Rodriguez-Porcel, Francisco Rivera, Claudio Daniel Gonzalez, Samantha Barkan, Susmit Tripathi, Emilia Gatto, Pedro Garcia Ruiz, Rare Movement Disorders Study Group of the International Parkinsons and Movement Disorders Society Source Type: research