Asprosin improved neuronal survival by suppressing apoptosis and enhancing the activity of the autophagy pathway in the MCAO model in rats

CONCLUSIONS: Asp has protective and therapeutic effects against CI/R damage. While applying Asp before ischemia activates the autophagy pathway more, applying it after ischemia protects the neuronal death/survival balance by activating the apoptosis pathway more.PMID:38497877 | DOI:10.26355/eurrev_202403_35608
Source: Pharmacological Reviews - Category: Drugs & Pharmacology Authors: Source Type: research