Prelimbic cortical pyramidal neurons to ventral tegmental area projections promotes arousal from sevoflurane anesthesia

CONCLUSION: This study demonstrates that PrLPyr neurons and their projections to the VTA are involved in facilitating emergence from sevoflurane anesthesia, with the PrLPyr -VTA pathway exerting its effects through the activation of NMDA receptors within the VTA.PMID:38488453 | PMC:PMC10941502 | DOI:10.1111/cns.14675

Source: CNS Neuroscience and Therapeutics - March 15, 2024 Category: Neuroscience Authors: Fuyang Cao Yongxin Guo Shuting Guo Xinyu Hao Lujia Yang Jiangbei Cao Zhikang Zhou Weidong Mi Li Tong Source Type: research