Involvement of Fgf2-mediated tau protein phosphorylation in cognitive deficits induced by sevoflurane in aged rats

CONCLUSION: Sevoflurane elicits a surge in Fgf2 expression in aging rats, directing tau protein phosphorylation through the PI3K/AKT/Gsk3b route, instigating cognitive aberrations.PMID:38493090 | DOI:10.1186/s10020-024-00784-0

Source: Molecular Medicine - March 17, 2024 Category: Molecular Biology Authors: Xin Xie Xiaomin Zhang Songze Li Wei Du Source Type: research