Roles of ghrelin, hepcidin and HIF-2 α in iron metabolism in iron deficiency anemia

ConclusionThe study suggests that the low hepcidin levels in IDA patients enhance iron absorption. The lack of significant HIF-2 α level differences may be due to the absence of chronic hypoxia in current hemoglobin levels of IDA patients. Moreover, the low ghrelin levels in patients and the correlations between ghrelin, hepcidin, and HIF-2α in both groups indicate their involvement in iron metabolism.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research