Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Left Main Disease With or Without Diabetes: Findings From a Pooled Analysis of 4 Randomized Clinical Trials

CONCLUSIONS: In patients with left main disease considered equally suitable for PCI or CABG and with largely low to intermediate SYNTAX scores, diabetes was associated with higher rates of death and cardiovascular events through 5 years. Compared with CABG, PCI resulted in no difference in the risk of death, a lower risk of early stroke regardless of diabetes status, and a higher risk of spontaneous MI and repeat coronary revascularization, with larger late absolute excess risks in patients with diabetes.REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifiers: NCT01205776, NCT0146651, NCT00422968, and NCT00114972.PMID:38465592 | DOI:10.1161/CIRCULATIONAHA.123.065571

Source: Circulation - March 11, 2024 Category: Cardiology Authors: Prakriti Gaba Joseph F Sabik Sabina A Murphy Andrea Bellavia Patrick T O'Gara Peter K Smith Patrick W Serruys A Pieter Kappetein Seung-Jung Park Duk-Woo Park Evald H Christiansen Niels R Holm Per H Nielsen Marc S Sabatine Gregg W Stone Brian A Bergmark Source Type: research