Isolated massive pleural effusion as a manifestation of chronic graft versus host disease successfully treated with corticosteroid

AbstractIsolated pleural effusion is a rare manifestation of chronic graft versus host disease  (cGVHD) after hematopoietic stem cell transplantation (HSCT). We herein report a 58-year-old woman presenting with massive pleural effusion approximately 1 year after allogeneic HSCT, who was successfully treated with corticosteroid. She had discontinued tacrolimus approximately 1 month before s he presented with pleural effusion, which was attributed to cGVHD after a thorough exclusion process. This case illustrates a unique manifestation of atypical cGVHD and highlights the need for prompt therapy initiation.
Source: Annals of Hematology - Category: Hematology Source Type: research