Study of the mechanism of acupuncture and moxibustion in protecting the intestinal mucosal barrier in DSS-induced UC rats based on the IL-9/IL-9R pathway

ConclusionBoth HM and EA can inhibit the protein expression levels of IL-9 and IL-9R in the UC colon by regulating the transcription factor PU.1, promote the repair of intestinal mucosal barrier, and down-regulate protein contents of proinflammatory factors IL-9, IL-6, and IL-1 β in the serum, which may be one of the key mechanisms of acupuncture and moxibustion in reducing the inflammation of UC colonic mucosa and protecting the intestinal mucosal barrier.
Source: Journal of Acupuncture and Tuina Science - Category: Complementary Medicine Source Type: research