Cancers, Vol. 16, Pages 1153: Sentinel Lymph Node Biopsy (SLNB) for Early-Stage Head and Neck Squamous-Cell Carcinoma of the Tongue: Twenty Years of Experience at I.N.T. & ldquo;G.Pascale & rdquo;

This study, conducted at the ENT and Maxillofacial Surgery department of the Istituto Nazionale Tumori in Naples, explores SLNB’s efficacy in early-stage oral tongue squamous-cell carcinoma (OTSCC). From January 2020 to January 2022, 122 T1/T2 cN0 HNSCC patients were enrolled. Radioactive tracers and lymphoscintigraphy identified sentinel lymph nodes, aided by a gamma probe during surgery. Results revealed 24.6% SLN biopsy positivity, with 169 SLNs resected and a 21.9% positivity ratio. The study suggests SLNB’s reliability for T1-2 cN0 OTSCC patient staging and early micrometastasis detection.

Source: Cancers - March 14, 2024 Category: Cancer & Oncology Authors: Franco Ionna Ettore Pavone Corrado Aversa Francesco Maffia Raffaele Spinelli Emanuele Carraturo Giovanni Salzano Fabio Maglitto Marco Sarcinella Roberta Fusco Vincenza Granata Secondo Lastoria Francesco Del Prato Maria Grazia Maglione Tags: Article Source Type: research