A Review of the Evolution of Quality of Life Measures in Head and Neck Cancer Clinical Trials

To best study the complex toxicity profiles experienced by patients treated with radiotherapy (RT) for head and neck (HN) cancer, a greater focus on quantifiable, reproducible quality of life (QOL) measures is needed. Both clinician-rated outcomes (CRO) and patient-reported outcome (PRO) measures of toxicity and QOL have been collected in HN clinical trials for over two decades. A clear understanding of existing PRO practices in these studies may inform future study design and spark innovative QOL-focused hypothesis-generating research.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: 201 Source Type: research