Visual evoked potentials in multiple sclerosis: P100 latency and visual pathway damage including the lateral geniculate nucleus

CONCLUSIONS: P100-latency is affected by anterior and posterior visual pathway damage. In ON-patients, damage at the synapse-level (LGN) may additionally contribute to latency delay.SIGNIFICANCE: Our findings corroborate post-chiasmatic contributions to the VEP-signal, which may relate to distinct pathophysiological mechanisms in MS.PMID:38461596 | DOI:10.1016/j.clinph.2024.02.020

Source: Clinical Neurophysiology - March 10, 2024 Category: Neurology Authors: Athina Papadopoulou Armanda Pfister Charidimos Tsagkas Laura Gaetano Shaumiya Sellathurai Marcus D'Souza Nuria Cerd á-Fuertes Konstantin Gugleta Maxime Descoteaux Mallar M Chakravarty Peter Fuhr Ludwig Kappos Cristina Granziera Stefano Magon Till Sprenge Source Type: research