Targeting gut microbiota to counteract acetaminophen-induced acute liver injury

Trends Microbiol. 2024 Mar 11:S0966-842X(24)00051-9. doi: 10.1016/j.tim.2024.02.011. Online ahead of print.ABSTRACTAcetaminophen (N-acetyl-p-aminophenol; APAP) overdose-induced acute liver injury (AILI) is a huge threat to public health worldwide. Recent research clearly shows that the intestinal microbiota (IM) is a key modulator in AILI. Herein, I discuss the latest findings on how the IM regulates AILI and the potential interventions to combat AILI by targeting the IM.PMID:38472076 | DOI:10.1016/j.tim.2024.02.011

Source: Trends in Microbiology - March 12, 2024 Category: Microbiology Authors: Peng Chen Source Type: research