Elucidation of the key therapeutic targets and potential mechanisms of Andrographolide multi-targets against osteoarthritis via network pharmacological analysis and experimental validation

CONCLUSION: This study provides a comprehensive understanding of the potential therapeutic targets and mechanisms of action of Andrographolide in OA treatment. Our findings suggest that Andrographolide is a promising candidate for drug development in the management of OA.PMID:38462021 | DOI:10.1016/j.gene.2024.148351

Source: Gene - March 10, 2024 Category: Genetics & Stem Cells Authors: Tengyun Yang Tingting Cao Xianguang Yang Guoliang Wang Yanlin Li Source Type: research