Early effects of different brain radiotherapy modalities on circulating leucocyte subpopulations in rodents

CONCLUSIONS: Leucocyte subpopulations reacted differently to X-ray or proton brain irradiation. This difference could be partly explained by LN exposure to radiation dose. Further researches and analyses on other biological processes and interactions between leucocyte subpopulations are ongoing. The various mechanisms underlying leucocyte subpopulation changes under different irradiation modalities may have implications for the choice of radiotherapy modalities and their combination with immunotherapy in brain cancer treatment.PMID:38466699 | DOI:10.1080/09553002.2024.2324471

Source: International Journal of Radiation Biology - March 11, 2024 Category: Radiology Authors: Thao-Nguyen Pham Julie Coupey J érôme Toutain Serge M Cand éias Ga ël Simonin Marc Rousseau Omar Touzani Juliette Thariat Samuel Valable Source Type: research