Revisiting the determinants of malaria transmission

Trends Parasitol. 2024 Mar 4:S1471-4922(24)00026-6. doi: 10.1016/j.pt.2024.02.001. Online ahead of print.ABSTRACTMalaria parasites have coevolved with humans over thousands of years, mirroring their migration out of Africa. They persist to this day, despite continuous elimination efforts worldwide. These parasites can adapt to changing environments during infection of human and mosquito, and when expanding the geographical range by switching vector species. Recent studies in the human malaria parasite, Plasmodium falciparum, identified determinants governing the plasticity of sexual conversion rates, sex ratio, and vector competence. Here we summarize the latest literature revealing environmental, epigenetic, and genetic determinants of malaria transmission.PMID:38443304 | DOI:10.1016/j.pt.2024.02.001
Source: Trends in Parasitology - Category: Parasitology Authors: Source Type: research