CADHERIN-11 regulation of myeloid phagocytes and autoimmune inflammation in murine lupus

CONCLUSION: This study highlights a novel role of CDH11 in regulating myeloid cells and efferocytosis and its potential as a contributor to development in autoimmunity murine lupus. Despite the increase in autoimmunity, Cdh11-/- mice developed decreased tissue inflammation and damage.PMID:38447248 | DOI:10.1016/j.jaut.2024.103197

Source: Journal of Autoimmunity - March 6, 2024 Category: Allergy & Immunology Authors: Thandiwe Chavula Sarah To Jennifer Smith Mesias Pedroza Jena Nimri Sridevi Devaraj Scott Wenderfer Tiphanie P Vogel Sandeep K Agarwal Source Type: research