Non-clinical toxicity and immunogenicity evaluation of a Plasmodium vivax malaria vaccine using Poly-ICLC (Hiltonol ®) as adjuvant

In conclusion, in these non-clinical models, repeated dose administrations of the PvCSP-All epitopes vaccine adjuvanted with a Poly-ICLC were immunogenic, safe, and well tolerated.PMID:38448321 | DOI:10.1016/j.vaccine.2024.02.070

Source: Vaccine - March 6, 2024 Category: Allergy & Immunology Authors: Rodolfo F Marques Alba M Gimenez Ot ávia Caballero Andrew Simpson Andres M Salazar Rogerio Amino Steven Godin Ricardo T Gazzinelli Irene S Soares Source Type: research