Suppressor of cytokine signaling 3-derived peptide as a therapeutic for inflammatory and oxidative stress-induced damage to the retina

CONCLUSIONS: R9-SOCS3-KIR blocks the induction of inflammatory signaling in cell culture and reduces retinal damage in a widely used RPE/retinal oxidative injury model. As this peptide can be administered through corneal instillation, this treatment may offer a convenient way to slow down the progression of ocular diseases arising from inflammation and chronic oxidative stress.PMID:38264613 | PMC:PMC10805335

Source: Molecular Vision - January 24, 2024 Category: Molecular Biology Authors: Chulbul M Ahmed Anil P Patel Howard M Johnson Cristhian J Ildefonso Alfred S Lewin Source Type: research