The prognostic role of histomorphological subtyping in nonmetastatic papillary renal cell carcinoma after curative surgery: is subtype really irrelevant? A propensity score matching analysis of a multi-institutional real life data

CONCLUSIONS: This multiinstitutional study suggested that type 2 was associated with adverse histopathologic outcomes, and predictor of RFS and CSS after surgical treatment of nonmetastatic papRCC, in overall cohort. In propensity score-matching cohort, type 2 remained the predictor of RFS. Eventhough 5th WHO classification for renal tumors eliminated histomorphological subtyping, these findings suggest that subtyping is relevant from the point of prognostic view.PMID:38443238 | DOI:10.1016/j.urolonc.2024.01.028

Source: Urologic Oncology - March 5, 2024 Category: Urology & Nephrology Authors: Selcuk Erdem Riccardo Bertolo Riccardo Campi Umberto Capitanio Daniele Amparore Umberto Anceschi Maria Carme Mir Eduard Roussel Nicola Pavan Umberto Carbonara Onder Kara Tobias Klatte Michele Marchioni Angela Pecoraro Stijn Muselaers Laura Marandino Pietr Source Type: research