Dissecting the causal relationship between neuroticism and osteoarthritis: a univariable and multivariable Mendelian randomization study

ConclusionsNeuroticism has significant causal effects on knee OA risk. Smoking might partly mediate the causal relationship. Further studies were warranted to explore the underlying mechanisms and potential use of neuroticism management for OA treatment.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research