Massive hemoptysis in pregnancy due to invasive pulmonary aspergillosis with pulmonary tuberculosis co ‐infection

In this case report, we present the challenging management of a second-trimester pregnancy in an immunocompromised individual who experienced life-threatening hemoptysis due to invasive pulmonary aspergillosis (IPA) accompanied by a co-infection of pulmonary tuberculosis (PTB). AbstractA 37-year-old woman, 25  weeks pregnant, experienced sudden massive hemoptysis. She had a background history of systemic lupus erythematosus (SLE) and past pulmonary tuberculosis (PTB). Emergency intubation was necessary, and bronchoscopy revealed blood pooling in both main bronchi, with active bleeding from the right up per lobe bronchus. Urgent computed tomography (CT) angiography of the bronchial artery identified a bleeding source and was successfully embolized. Antifungal and anti-tuberculous therapy was initiated based on bronchoalveolar lavage results. Despite initial improvement, hemoptysis recurred after th e third week, leading to repeat embolization, followed by a caesarean section and right upper lobectomy. Both mother and baby survived, remaining well at a 6-week follow-up, emphasizing the complexities of managing recurrent hemoptysis during pregnancy and potential drug interactions.
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: CASE REPORT Source Type: research