Adeno-associated virus –mediated gene therapy for cardiac tachyarrhythmia: A systematic review and meta-analysis

Cardiac tachyarrhythmia presents a significant health care challenge, causing notable morbidity and mortality. Conventional treatments have limitations and potential risks, resulting in an elevated disease burden. Adeno-associated virus (AAV) –mediated gene therapy holds promise as a potential future treatment option. Therefore, we aimed to provide a measured overview of the latest developments in this rapidly growing field. PubMed and Embase databases were searched up to January 2024. Studies that employed AAV as a vector for delivery of therapeutic agents to treat cardiac tachyarrhythmia were included.
Source: Heart Rhythm - Category: Cardiology Authors: Tags: Contemporary Review Source Type: research