Relationship of the < em > 1846G < /em > & gt; < em > A < /em > Polymorphism of the < em > CYP2D6 < /em > Gene to the Equilibrium Concentration Levels of Haloperidol in Patients with Acute Alcoholic Hallucinosis

CONCLUSION: It can be concluded that patients with the GA genotype have a higher risk of ADRs compared to patients carrying the GG genotype. It is shown that 1846G > A polymorphism of the CYP2D6 gene (rs3892097) has a statistically significant effect on the equilibrium concentration levels of haloperidol.PMID:38076663 | PMC:PMC10698856

Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: A A Parkhomenko M S Zastrozhin VYu Skryabin A E Petukhov S A Pozdniakov V A Ivanchenko I A Zaytsev I V Bure P O Bochkov K A Akmalova V V Smirnov E A Bryun D A Sychev Source Type: research