Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health

CONCLUSIONS: This study reveals that the prevalence of germline mutations in the BRCA1 and BRCA2 genes was higher than reported by other studies. A broader understanding of the prevalence and role of BRCA mutations in development, response to treatment, and prognosis represents an exciting and developing area of ovarian cancer treatment and prevention.PMID:38386807 | PMC:PMC10883683 | DOI:10.18632/oncotarget.28561

Source: Oncotarget - February 22, 2024 Category: Cancer & Oncology Authors: Elisabetta De Matteis Maria Rosaria Tumolo Paolo Tarantino Mariangela Ciccarese Tiziana Grassi Francesco Bagordo Maria Rita De Giorgio Emanuele Rizzo Graziana Ronzino Source Type: research